Gonzalo de Prat Gay

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Lucia Beatriz ChemesInvestigadora Independiente, CONICET, ArgentinaVerified email at iib.unsam.edu.ar
Ignacio Enrique SanchezCONICET researcher, Universidad de Buenos Aires (Argentina)Verified email at qb.fcen.uba.ar
Alan FershtEmeritus Group Leader, MRC Laboratory of Molecular Biology, University of CambridgeVerified email at cam.ac.uk
Alejandro Daniel NadraUBA - CONICETVerified email at qi.fcen.uba.ar
Diego U. FerreiroCONICET, FCEyN, Universidad de Buenos AiresVerified email at qb.fcen.uba.ar
Mariano DellaroleCIBION, CONICET (Argentina)Verified email at cibion.conicet.gov.ar
Mok YKAssociate Professor of Biological Sciences, National University of SingaporeVerified email at nus.edu.sg
Andreas LadurnerChair of Physiological Chemistry, LMU Munich; Founder, Managing Director and CSO, Eisbach Bio GmbHVerified email at med.lmu.de
Juliana GlavinaPost-Doctoral. FONCyT, ArgentinaVerified email at iib.unsam.edu.ar
Fabio Ceneviva Lacerda de AlmeidaProfessor of Biochemistry, Federal University of Rio de JaneiroVerified email at bioqmed.ufrj.br
Jerson L. SilvaProfessor of Biochemistry, Universidade Federal do Rio de JaneiroVerified email at bioqmed.ufrj.br
Cristina Marino BusljeResearcher, Nat. Research Council (CONICET). Head of the Bioinformatics Unit.Fundación InstitutoVerified email at leloir.org.ar
Luis Mauricio T R LimaProfessor of Structural Biology, Federal University of Rio de Janeiro - UFRJ - BrazilVerified email at UFRJ.BR
Laura MorelliCONICETVerified email at leloir.org.ar
Alison McBridenational institutes of healthVerified email at nih.gov
Guilherme A. P. de OliveiraAssociate Professor, Medical Biochemistry Institute Leopoldo de Meis, National Institute ofVerified email at bioqmed.ufrj.br
Ashley BuckleReplayVerified email at replay.bio
Debora FoguelProfessor Titular, Universidade Federal do Rio de JaneiroVerified email at bioqmed.ufrj.br
Gastón ParisCentro de Investigaciones en BionanocienciasVerified email at cibion.conicet.gov.ar
Julian FaivovichDivisión Herpetología, Museo Argentino de Ciencias Naturales-CONICETVerified email at macn.gov.ar

Gonzalo de Prat Gay

Head, Protein Structure-Function and Engineering Lab, Fundación Instituto Leloir-CONICET, Argentina

Verified email at leloir.org.ar

Virus biomolecular condensates intrinsically disordered proteins protein folding assembly and interactions


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Nuclease activity of the Junin virus nucleoprotein C-terminal domain AA Sierra, ME Loureiro, S Esperante, SS Borkosky, GL Gallo, ... Viruses 15 (9), 1818, 2023	1	2023
Molten globule driven and self-downmodulated phase separation of a viral factory scaffold M Salgueiro, G Camporeale, A Visentin, M Aran, L Pellizza, SA Esperante, ... Journal of Molecular Biology 435 (16), 168153, 2023	4	2023
Biomolecular condensation of the human papillomavirus E2 master regulator with p53: implications in viral replication SS Borkosky, M Fassolari, K Campos-León, AH Rossi, M Salgueiro, ... Journal of Molecular Biology 435 (16), 167889, 2023	4	2023
Assembly of the Tripartite and RNA Condensates of the Respiratory Syncytial Virus Factory Proteins In Vitro: Role of the Transcription Antiterminator M_2-1 A Visentin, N Demitroff, M Salgueiro, SS Borkosky, VN Uversky, ... Viruses 15 (6), 1329, 2023	2	2023
Nuclease Activity of the Junín Virus Nucleoprotein C-Terminal Domain AB Armella Sierra, ME Loureiro, S Esperante, SS Borkosky, GL Gallo, ... MDPI, 2023		2023
Molten Globule Driven and Self-downmodulated Phase Separation of a Viral Factory Scaffold: Phase separation of a viral replication scaffold M Salgueiro, G Camporeale, AN Visentin, M Aran, LA Pellizza Pena, ... Academic Press Ltd-Elsevier Science Ltd, 2023		2023
A finely tuned interplay between calcium binding, ionic strength and pH modulates conformational and oligomerization equilibria in the Respiratory Syncytial Virus Matrix (M … SA Esperante, D Alvarez-Paggi, M Salgueiro, MF Desimone, ... Archives of biochemistry and biophysics 731, 109424, 2022		2022
Conformational buffering underlies functional selection in intrinsically disordered protein regions NS Gonzalez-Foutel, J Glavina, WM Borcherds, M Safranchik, ... Nature structural & molecular biology 29 (8), 781-790, 2022	48	2022
The guardian of the genome meets a viral master gene regulator at a biomolecular condensate SS Borkosky, M Fassolari, K Campos-León, AH Rossi, M Salgueiro, ... bioRxiv, 2022.02. 09.479752, 2022	2	2022
Deconstructing virus condensation N Lopez, G Camporeale, M Salgueiro, SS Borkosky, A Visentín, ... PLoS pathogens 17 (10), e1009926, 2021	51	2021
Liquid-like condensates of p53 are modulated by interaction with the papillomavirus E2 master regulator S Borkosky, K Campos-Leon, R Peralta Martinez, N Demitroff, K Gaston, ... PROTEIN SCIENCE 30, 112-113, 2021		2021
Molten Globule Driven Liquid-Liquid Phase Separation at the Center of Viral Factory Assembly M Salgueiro, G Camporeale, J Conci, B Sousa, A Visentin, A Corbat, ... Biophysical Journal 118 (3), 215a, 2020	1	2020
The structure of the extended E2 DNA‐binding domain of the bovine papillomavirus‐1 L Leroy, JARG Barbosa, G de Prat‐Gay, I Polikarpov, CB Pinheiro Proteins: Structure, Function, and Bioinformatics 88 (1), 106-112, 2020	1	2020
A conformational switch balances viral RNA accessibility and protection in a nucleocapsid ring model DA Paggi, SA Esperante, M Salgueiro, G Camporeale, GAP De Oliveira, ... Archives of biochemistry and biophysics 671, 77-86, 2019	7	2019
Topology dictates evolution of regulatory cysteines in a family of viral oncoproteins D Alvarez-Paggi, JR Lorenzo, G Camporeale, L Montero, IE Sánchez, ... Molecular Biology and Evolution 36 (7), 1521-1532, 2019	7	2019
Conformational isomerization involving conserved proline residues modulates oligomerization of the NS1 interferon response inhibitor from the syncytial respiratory virus J Conci, D Alvarez-Paggi, GAP de Oliveira, TD Pagani, SA Esperante, ... Biochemistry 58 (26), 2883-2892, 2019	3	2019
Interplay between sequence, structure and linear motifs in the adenovirus E1A hub protein J Glavina, EA Román, R Espada, G de Prat-Gay, LB Chemes, IE Sánchez Virology 525, 117-131, 2018	15	2018
Mechanism of Tetramer Dissociation, Unfolding, and Oligomer Assembly of Pneumovirus M2-1 Transcription Antiterminators SA Esperante, D Alvarez-Paggi, M Salgueiro, G Prat Gay ACS omega 3 (11), 14732-14745, 2018	7	2018
Cooperative RNA recognition by a viral transcription antiterminator IG Molina, SA Esperante, C Marino-Buslje, LB Chemes, G de Prat-Gay Journal of Molecular Biology 430 (6), 777-792, 2018	12	2018
Structure and stability of the Human respiratory syncytial virus M2–1 RNA-binding core domain reveals a compact and cooperative folding unit IG Molina, I Josts, Y Almeida Hernandez, S Esperante, M Salgueiro, ... Acta Crystallographica Section F: Structural Biology Communications 74 (1 …, 2018	6	2018

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